CORDIS Project
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This project focuses on improving drug delivery to tumors, particularly in desmoplastic cancers, by combining mechanotherapeutics and ultrasound sonopermeation. The goal is to enhance treatment efficacy and patient outcomes through optimized strategies that address tumor microenvironment challenges.
Inefficient drug delivery to tumors can reduce dramatically treatment efficacy and thus, affect negatively the life of cancer patients.
This is particularly evident in desmoplastic cancers where interactions among cancer cells, stromal cells and the fibrotic matrix cause tumor stiffening and accumulation of mechanical forces that compress tumor blood vessels.
Indeed, in subsets of pancreatic cancers and sarcomas, 95% of intratumoral blood vessels may be compressed and up to 80% totally collapsed…
THE CYPRUS FOUNDATION FOR MUSCULAR DYSTROPHY RESEARCH CYRUS INSTIT OF NEURO & GENETICS
KYPRIAKO IDRYMA EREVNON GIA TI MYIKI DISTROFIA
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Cyprus, Nicosia
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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