CORDIS Project
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This project addresses the challenges of drug development by introducing a novel bioreactor that integrates a 3D substrate for stem cell culture. The aim is to improve drug testing accuracy by simulating complex biological interactions, thus reducing the high failure rate in drug efficacy.
The problem that we address is that the pharmaceutical companies do not develop radically new drugs anymore, because the development process lasts ten years and costs around one billion euro.
Development of a new drug is subjected to regulatory approvals following three demonstrations: lab discovery in vitro, animal testing in vivo and clinical trial on patients.
This process has 99.9% overall failure, of which 96.4% because the drug efficacy measured in vitro is not confirmed in animals.
In fac…
POLITECNICO DI MILANO
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UNIVERSITA' DEGLI STUDI DI BERGAMO
Italy, Bergamo
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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