CORDIS Project
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This project focuses on the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, aiming to develop therapeutic agents that stabilize its function. By studying the protein's structure and dynamics, it seeks to design drugs that can restore its chloride channel activity, addressing cystic fibrosis-related…
The CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) is a unique ABC protein functioning as a chloride channel.
It consists of two transmembrane and two nucleotide binding domains, and a regulatory region.
The cftr gene is mutated in cystic fibrosis, an inherited disease of high morbidity and mortality mostly affecting people with European ancestors.
So far more than 1,500 mutations are known affecting the stability or the function of the protein that results in the lack of functional…
HUN REN TAMOGATOTT KUTATOCSOPORTOK IRODAJA
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