CORDIS Project
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This project focuses on developing a genetic therapy to address mitochondrial dysfunction, which is linked to various human diseases, including neurodegenerative conditions and metabolic disorders. By utilizing alternative respiratory chain enzymes, it aims to restore normal metabolic functions in affected cells.
Defects in the primary metabolic functions of mitochondria, the cell’s‘power-plants’, underlie a diverse range of human pathologies, includingrare neuromuscular syndromes, many cases of common multifactorialdiseases (e.g epilepsy, deafness, diabetes), neurodegenerativeconditions such as Parkinson’s disease (PD), and devastating metabolicdisorders of infancy.
Mitochondrial dysfunction is also a major cause oftissue damage in heart attack and stroke, and is involved incancer progression.
This proj…
TAMPEREEN YLIOPISTO
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