CORDIS Project
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This project investigates the molecular mechanisms behind heart failure, focusing on how mechanical strain affects heart cells. By studying key proteins involved in cell protection, it aims to uncover new therapeutic targets for improving heart function.
Chronic heart failure is a leading cause of mortality in the industrialized countries.
Pathomechanistically, a variety of diverse stress signals on the cardiomyocyte trigger loss of myofibrils and cardiomyocyte death, thereby activating a vicious cycle of cardiac stress and deterioration during terminal heart failure.
Despite the enormous clinical relevance, the exact pathomechanisms in charge remains unclear.Here, I propose to investigate the molecular mechanisms that couple mechanical cardiomy…
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LOS ANGELES UCLA SANTA BARBARA UCSB DAVIS UCD RIVERSIDE UCR SAN DIEGO UCSD SANTA CRUZ UCSC IRVIN
United States, Berkeley
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Germany, Heidelberg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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