CORDIS Project
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This project aims to understand gene expression regulation during embryonic development, focusing on core promoter elements that control transcription. It investigates the role of specific transcription factors in regulating developmental genes, particularly Hox genes.
The regulation of gene expression at the level of transcription is critical during development and growth of an organism.
Specifically, regulation of embryonic development depends on complex gene networks.
At the transcription level, embryonic segmentation relies on transcription factor gradients, sequence-specific DNA-binding proteins and regulatory DNA sequences such as enhancers.
These enhancers recruit transcriptional activators, resulting in the recruitment of RNA polymerase II and the gene…
BAR ILAN UNIVERSITY
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