CORDIS Project
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This project aims to create a novel approach in medicinal chemistry by developing personalized drug delivery systems that utilize RNA biomarkers from cancer cells. By employing specific chemical reactions, the project seeks to enhance the effectiveness of cancer treatments while addressing issues of selectivity and dru…
In this proposal we intend to develop a new medicinal chemistry concept base on cell-personalized delivery of tailored drugs.
Relying on basic chemical tools such as proximity-induced acyl transfer reactions and catalytic turnover- we will use RNA biomarkers of cancer cells to trigger the specific expression of cytotoxic drugs.
This approach, in addition to contribute to basic science in chemistry and chemical and cell biology and suggest new therapeutic strategies, might allow to overcome the m…
HUMBOLDT-UNIVERSITAET ZU BERLIN
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