CORDIS Project
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This project investigates the interactions between adeno-associated virus vectors and the human immune system to enhance the safety and effectiveness of gene therapy. By understanding immune responses, the aim is to improve long-lasting gene transfer for inherited disorders, addressing challenges posed by immune reacti…
Experience with adeno-associated virus (AAV) vector-mediated gene transfer in human trials has unveiled the therapeutic potential of this approach, with some of the most exciting results coming from clinical studies of gene transfer for hemophilia B, congenital blindness, and the recent market approval of the first AAV-based gene therapy in Europe.
Follow-up data of subjects treated with AAV vectors is showing sustained correction of the disease phenotype for several years after gene transfer, a…
ASSOCIATION GENETHON
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France, PARIS
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
France, Paris
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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