CORDIS Project
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This project investigates the role of FASTKD2 proteins, a newly identified family of RNA-binding proteins, in regulating mitochondrial function. By characterizing their RNA interactions, the research aims to uncover their biological significance and potential implications for health and disease.
Posttranscriptional gene regulation is an essential process exerted by a multitude of RNA-binding proteins (RBPs) and allows for rapid adaptation of the cellular proteome to environmental perturbations.
Previously, only in a limited number of instructive cases, the RNA networks targeted by individual RBPs had been elucidated.
The recent proteome-wide unbiased identification of RBPs yielded a comprehensive catalogue of RBPs acting in human cells and has assigned an RNA-binding activity to over 30…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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