CORDIS Project
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This project focuses on developing a new microscopy technique to study synaptic function in living neurons with high spatial and temporal resolution. The goal is to enable long-term imaging of neuronal processes, enhancing our understanding of synaptic transmission and related cellular dynamics.
Synaptic function is difficult to analyze in living neurons using conventional optics, since the synaptic organelles and protein clusters are small and tightly spaced.
The solution to this problem can come from the field of super-resolution fluorescence microscopy, or nanoscopy.
However, the current approaches to nanoscopy are still far from reaching this goal.
Single molecule-based approaches (including STORM and PALM) provide high spatial resolution, but slow recording, insufficient for live i…
KUNGLIGA TEKNISKA HOEGSKOLAN
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