CORDIS Project
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This project investigates the molecular processes of aging, specifically focusing on the role of Methionine oxidation in cellular lifespan. It aims to develop imaging techniques to visualize the repair mechanisms of Methionine oxidation in live bacteria, enhancing our understanding of aging.
Identifying the causal molecular processes of aging is a long-standing quest in biology.
Oxidative stress is a conserved hallmark of senescence among living organisms, but the underlying mechanisms linking oxidative damage and aging have proved difficult to unravel.
Multiple reports pinpoint Methionine oxidation as an important antioxidant system influencing the lifespan of cells.
Here, I propose to develop an approach including single-particle tracking and microfludic-based single-cell imaging…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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