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The morphoPRINT project aims to develop a dynamic hydrogel platform that enables bioprinted tissues to undergo programmable shape changes. By manipulating volumetric growth, the project seeks to recreate the morphogenetic processes essential for organ development, specifically focusing on designing bioprinted heart tub…
During embryonic development, organs emerge through highly dynamic processes driven by complex shape-transformations that sculpt their final shape, composition, and function.
Despite this, existing approaches to organ bioprinting employ static hydrogels that are not capable of supporting morphogenetic shape changes.
Further, we lack an understanding of how key morphogenetic forces such as volumetric tissue growth can be leveraged to re-engineer fundamental tissue shape-morphing behaviours such a…
UNIVERSITY OF GALWAY
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