CORDIS Project
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This project investigates the mechanistic target of rapamycin (mTOR) pathway, focusing on its role in cellular growth and metabolism. By studying RNA-binding proteins and their interactions with RNA, the research aims to uncover new insights into the regulatory mechanisms of mTOR in health and disease.
The mechanistic target of rapamycin (mTOR) is a highly conserved serine/threonine kinase in eukaryotic organisms. mTOR is the catalytic subunit of two different complexes (mTORC1 and mTORC2), which differ by their subcellular localization and function.
The mTORCs integrate the environmental and cellular signal and regulate a broad range of downstream growth events.
Impaired regulation of mTOR was often observed in tumors, Alzheimer’s disease, several metabolic disorders, and is known to accelera…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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