CORDIS Project
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This project seeks to enhance the detection of protein biomarkers using innovative electrical assays based on peptide aptamers. These assays aim to provide high sensitivity and multiplexing capabilities for analyzing complex biological samples, improving the efficiency of protein microarrays.
The detection and quantification of protein biomarkers in biological samples lies central to proteomics, drug design, disease prognosis and therapeutic development.
The generation of viable protein microarrays is, though, challenging.
The first protein microarrays were built onantibodies.
Unfortunately antibodies do not function well in the microarray format, because typically only a small fraction (20%) specifically recognizes the target protein.
Current antibody based optical assays are common…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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