CORDIS Project
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This project investigates the functions of monocytes and macrophages in the immune system using advanced imaging techniques in live animals. It focuses on understanding the molecular mechanisms governing the behavior of tissue-resident immune cells, particularly Langerhans cells, during inflammation and homeostasis.
Leucocytes are hemopoietic cells involved in tissue homeostasis, inflammation, and the defence against infection.
Recent efforts have focused on the innate immune system , responsible for the early defence against pathogens, at the cost of tissue inflammation and inflammatory disease.
New tools and experimental strategies have allowed investigation of an essential component of the innate immune system: cells referred to as the mononuclear phagocyte system (MPS), which includes blood monocytes…
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