CORDIS Project
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This project investigates how messenger ribonucleoprotein particles (mRNPs) are formed and how their composition affects mRNA localization and translation in Drosophila embryos. By analyzing RNA binding proteins, the project aims to understand the mechanisms that control gene expression during development.
mRNAs are packed with RNA binding proteins (RBPs) to assemble the messenger ribonucleoprotein particles (mRNPs).
Proper mRNP biogenesis, export, localization, translation, and decay are central for gene expression regulation.
Each step requires specific RBPs mediating transcript interactions with the cellular machinery.
So far, hundreds of RBPs have been identified begging the question of mRNP assembly diversity.
While canonical RBPs are associated with all transcripts, some may be accessory, co…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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