CORDIS Project
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MRStain aims to enhance non-invasive brain imaging by using Magnetic Resonance Imaging to estimate histological metrics. This project focuses on validating MRI-based models against traditional histology methods, particularly in patients with drug-resistant temporal lobe epilepsy, to improve surgical outcomes and advanc…
Ex-vivo histology is the gold standard to investigate human brain microstructure.
However, its invasive nature precludes its use in monitoring disease progression and the investigation of the pathophysiological origin of neurological disorders. MRStain will address this shortcoming by exploiting the sensitivity of the Magnetic Resonance Imaging (MRI) signal to estimate aggregated histological metrics in the human brain non-invasively.
Like established histology staining methods (e.g., myelin-bas…
UNIVERSITÄTSKLINIKUM SCHLESWIG-HOLSTEIN
UNIVERSITATSKLINIKUM SCHLESWIG-HOLSTEIN
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Germany, Hamburg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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