CORDIS Project
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This project explores the mechanical aspects of tissue growth regulation using Drosophila wing discs. It aims to understand how mechanical forces influence signaling networks that control tissue size and morphology, with implications for cancer treatment.
The control of tissue size and morphology is a fundamental problem that is remarkably ill understood.
Although extensive research has focussed on the genetic and biochemical control of tissue growth, significantly less attention has been paid to the mechanical aspect of growth regulation, even though ample evidence indicates that any deformation or shape change is, to some degree, a result of force acting on a mass.
Unravelling the basis of the mechanical-biochemical co-regulation in tissue grow…
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