CORDIS Project
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This project investigates the mechanisms behind cancer metastasis, focusing on metastatic initiating cells. By developing new animal models and using advanced lineage tracing techniques, it aims to enhance understanding of tumor behavior and improve early diagnosis and treatment strategies.
Metastasis is the primary cause of cancer deaths.
For most cancers, the identification and the mechanisms by which the metastatic initiating cells (MICs) successfully establish a secondary tumour at a distant site from their primary tumour remains elusive (1).
New animal models are needed to better understand the clonal dynamic and molecular mechanisms guiding different steps of the metastatic cascades in vivo, given the tremendous heterogeneity of tumours (2-7) and the limited capacity to trace…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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Belgium, Bruxelles / Brussel
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Switzerland, Basel
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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