CORDIS Project
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This project investigates the efficacy of mesenchymal stem cell therapy for steroid-resistant acute Graft versus Host Disease. It explores the differences between licensed and unlicensed stem cells and aims to identify therapeutic efficacy correlates that could enhance treatment outcomes for patients undergoing stem ce…
Steroid resistant acute Graft versus Host Disease (GvHD) is a very serious complicationassociated with allogeneic haematopoietic stem cell transplantation.
There is no established consensus on the therapy for this disease and the prognosis for these patients is poor.
Early reports of MSC therapy for acute GvHD involving small numbers of patients were promising, however, results from large scale multi-centre phase III trials have questioned the therapeutic efficacy of MSC therapy for GvHD.
Our hy…
NATIONAL UNIVERSITY OF IRELAND MAYNOOTH
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