CORDIS Project
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The MT-PoINT project aims to enhance cancer immunotherapy by developing predictors for T cell-epitope interactions. By analyzing T cell sequences and their binding patterns, the project seeks to identify effective T cells for targeting cancer epitopes, utilizing extensive datasets from various sources, including patien…
T cells are a key element of the human immune system.
Upon binding to antigenic peptides (called T cell epitopes), T cells can induce the death of infected cells or prime and regulate other immune cells.
In cancer immunotherapy treatments, T cells are genetically re-engineered to recognize cancer epitopes and destroy malignant cells.
Unfortunately, it still remains challenging to determine which T cells can target a specific epitope, both from a computational and experimental point of view.
This…
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