CORDIS Project
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This project investigates the dynamics and function of microtubules in endothelial cells during sprouting angiogenesis, aiming to uncover the role of specific regulatory proteins. By using advanced imaging techniques and 3D culture models, it seeks to enhance understanding of angiogenesis and identify potential therape…
Restoring normal vessel structure and function is now considered as a highly promising therapeutic opportunity for angiogenesis-related diseases, including cancer.
Despite extensive use of microtubule targeting compounds in vascular-directed anticancer treatment, knowledge of the cellular mechanisms underlying microtubule regulation during angiogenesis is still elusive.
By combining my previous experience in endothelial cell biology and the long term expertise of the host laboratory in microtubu…
UNIVERSITEIT UTRECHT
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