CORDIS Project
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This project investigates the role of mucus secreting cells in the cervix during pregnancy, focusing on their function in creating a protective mucus plug. It aims to understand the factors influencing these cells and their implications for preterm birth and fetal health.
During pregnancy, the cervix undergoes dramatic remodelling characterised by the emergence of mucus secreting goblet cells (GCs) that generate a cervical mucus plug (CMP) in the cervical canal.
The CMP is thought to act as a barrier that is crucial for maintaining uterine sterility, thereby protecting the foetus from ascending bacterial infections.
However, this view is based on relatively little experimental evidence and our knowledge of specific endogenous or exogenous factors that may regulat…
UGOT - GOETEBORGS UNIVERSITET/UNIVERSITY OF GOTHENBURG
GOETEBORGS UNIVERSITET
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