CORDIS Project
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The MultiCloneSeq project aims to develop a cost-effective single-cell multi-omics sequencing tool to study cancer heterogeneity. This technology will enable simultaneous analysis of genetic mutations and RNA expression, improving cancer diagnosis and treatment strategies.
Cancer led to one in six death worlds wildly.
By nature, cancer is characterized by abnormal and uncontrolled cellular growth caused primarily by genetic mutations.
Despite of the high cellular heterogeneity, only a small number of somatic mutations shown to be directly associated with tumorigenesis, hence driving cancer growth.
The first hurdle in the cancer diagnosis is to identify these rare populations that have the potential to develop drug resistance. A second hurdle is to be able to assoc…
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