CORDIS Project
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This project advances genetically encoded voltage sensors to monitor neuronal activity with high temporal resolution. By enhancing the GEVOS technique, it aims to simultaneously observe multiple cell types, providing insights into brain circuit functions during inhibition.
Optogenetics are used to activate or silence specific sets of neurons, intracellular signaling pathways, or to examine brain structure at an unprecedented detail.
The only optogenetic approach lagging behind all others is the genetically encoded optical monitoring of multi-neuronal activity at a time resolution of single action potentials.
Such ultrafast (<1 ms) resolution is important to understand network function in healthy and diseased nervous systems because timing of neuronal firing and s…
UNIVERSITATSKLINIKUM BONN
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