CORDIS Project
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This project develops a mass spectrometry technique to analyze the vaginal microbiome, aiming to improve reproductive health diagnostics. It focuses on predicting success rates of in vitro fertilization and identifying patients at risk of premature birth through metabolomic analysis.
There is ever increasing evidence that the vaginal microbiome plays an important role in reproductive health.
Studies have shown that dysbiotic states can culminate in bacterial vaginosis, urinary tract infections and premature birth.
Although the microbiome is usually characterised by 16S rRNA sequencing, the methodology is time consuming and expensive.
Here we describe the development of a desorption ionisation mass spectrometry (DESI-MS) based technique which characterises microbial community…
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