CORDIS Project
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This project investigates the synthesis and secretion of mucins, key components of mucus, to understand their role in diseases like Inflammatory Bowel Diseases and Chronic Obstructive Pulmonary Disease. Using advanced gene-editing techniques, the research aims to uncover mechanisms of mucin sorting and packaging, poten…
Inflammatory Bowel Diseases (IBD) affected more than 6.8 million people worldwide in 2017, and Chronic Obstructive Pulmonary Disease(COPD) caused 3.23 million deaths in 2019.
Both illnesses present a disturbance in the quantity and quality of mucus due to an abnormal expression and secretion of mucins.
The mucins are the main component of mucus and are specifically expressed in cells and tissues.
Mucin secretion is crucial for the normal physiology of wet mucosal epithelium.
Growing data shows t…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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