CORDIS Project
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This project investigates the genetic basis of mitral valve prolapse, a common heart disorder. It aims to identify specific genes and mutations associated with the condition using advanced sequencing techniques to better understand its etiology.
Background:
Mitral valve prolapse (MVP) is one of the most common valvular heart disorders.
Twenty percent of MVP patients will develop severe complications, including congestive heart failure, endocarditis, atrial arrhythmias, embolic events and even sudden death. MVP is the most common cause of mitral regurgitation requiring surgical repair, however, very little is known about its etiology. MVP has a strong genetic background with significant heterogeneity.
Previous genetic studies have sho…
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