CORDIS Project
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This project aims to develop a new magnetic resonance imaging technique called Mesoscopic White-Matter Imaging (MWMI) to measure micro-scale metrics in brain white matter. It focuses on understanding the origins of microstructural changes related to learning and pain processing.
The goal of this highly multi-disciplinary and inter-sectional proposal is to develop a novel computational in-vivo MRI technique, namely Mesoscopic White-Matter magnetic resonance Imaging (MWMI). MWMI will measure 5 specific micro-scale metrics at a mesoscopic spatial resolution of about 300 μm: myelin, iron, water concentration, axonal density, and the ratio between inner and outer fiber diameter (g-ratio) - a surrogate measure for its conductance speed.
Conventional quantitative MRI (qMRI), s…
UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF
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