CORDIS Project
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This project investigates the role of the c-Myc transcription factor in macrophages related to atherosclerosis. It aims to understand how c-Myc influences macrophage functions such as proliferation and lipid uptake, which are critical in the development and progression of cardiovascular diseases.
Atherosclerosis and associated cardiovascular disease are the leading causes of mortality in developed countries and the World Health Organization has estimated that by 2020 these disorders will be the main sanitary and socio-economic problem world-wide due in part to the progressive aging of our societies.
Atherosclerosis is a complex chronic inflammatory process triggered and perpetuated by cardiovascular risk factors which cause endothelial dysfunction and leukocyte infiltration within the su…
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