CORDIS Project
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This project focuses on engineering a simplified bacterium, Mycoplasma pneumoniae, to create a versatile platform for delivering therapies and vaccines. By utilizing advanced modeling and genome engineering techniques, it aims to optimize bacterial chassis for medical applications, particularly in combating lung infect…
Engineering bacteria to deliver therapeutic agents or to present antigens for vaccination is an emerging area of research with great clinical potential.
The most challenging issue in this field is the selection of the right bacteria to engineer, commonly known as “chassis”.
The best chassis depends on the application but there is a common drawback in bacteria used nowadays: their complexity and the lack of quantitative information for many reactions which limits genome engineering to classical t…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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