CORDIS Project
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This project investigates the mechanisms behind treatment resistance in multiple myeloma by studying cancer stem cells and circulating tumor cells. It aims to identify genetic signatures and understand immune responses to improve therapeutic strategies for patients with minimal residual disease.
Multiple myeloma (MM) represents a unique model to investigate cancer stem cells (CSCs), circulating tumour cells (CTCs), and the mechanisms of malignant transformation and chemoresistance.
Despite the substantial improvement in MM patients’ outcome, the vast majority of patients eventually relapse and the disease remains largely incurable.
For those patients failing to achieve deep remissions, biologically targeted research on the ultra-chemoresistant minimal residual disease (MRD) clone may al…
UNIVERSIDAD DE NAVARRA
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