CORDIS Project
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This project aims to uncover the genetic and environmental factors contributing to myopia, particularly high myopia. By analyzing large datasets and conducting animal studies, it seeks to identify mechanisms and potential therapeutic targets to mitigate the disease.
Background:
Myopia (near-sightedness) is a growing public health issue due to its rapidly rising prevalence.
In particular high myopia carries a significant risk of blindness for which there are no treatment options.
The disease etiology of this trait is complex and largely unknown.
We recently identified a large number of disease loci and genes, which provide significant clues for pathogenic pathways.
However, they explain only a limited proportion of myopia’s heritability, and the direct funct…
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
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