CORDIS Project
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This project investigates the relationship between skeletal muscle and tumor growth in cancer patients suffering from cachexia. It aims to understand how activating specific pathways in muscle can influence tumor biology and identify muscle-secreted factors that affect tumor cells, potentially improving treatment outco…
Cachexia is a life-threatening condition characterized by a drastic loss in both muscle and adipose tissue, which is associated with several pathologies, including cancer.
In cancer patients, its prevalence is of 50-80%, and is the direct cause of at least 20% of cancer-associated deaths.
Cachectic patients show lower response rates to chemotherapy and a reduced tolerance to anticancer treatment, being of major clinical relevance.
So, while cachexia is clearly of great significance for disease p…
UNIVERSITA DEGLI STUDI DI PADOVA
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