CORDIS Project
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This project investigates a specific subtype of endothelial cells with immunomodulatory properties to enhance cancer immunotherapy. It aims to identify new drug targets through innovative artificial intelligence tools and rapid genetic modification techniques, ultimately improving treatment efficacy against cancer.
Compared to my previous Advanced ERC grants, this proposal is fundamentally different not only concerning its topic but also regarding its ambition to offer greater societal impact by coupling knowledge gain tighter to translation.
It promises to obtain new insights in an understudied endothelial cell (EC) subtype with immunomodulatory gene signatures (coined IMECs), highly relevant for alternative immunotherapy development.
Indeed, silencing immunosuppressive genes in IMECs offers unprece-dente…
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