CORDIS Project
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This project aims to develop a novel method for directly visualizing and quantifying the asymmetry of cell membranes. By combining advanced microscopy techniques with isotropic expansion methods, it will enhance our understanding of lipid dynamics during cellular processes, particularly in the context of viral infectio…
The compositional and structural asymmetry of cell membranes remains one of the greatest knowledge gaps in cell biology.
Cells invest significant amount of energy to establish and maintain inter-leaflet asymmetry; however, the physiological roles of bilayer lipids during dynamic cellular processes in eukaryote membranes remain poorly understood, mostly due to the limits of previously available methodologies and the complexity of lipid membranes.
Current knowledge originates from indirect and per…
KAROLINSKA INSTITUTET
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