CORDIS Project
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This project explores the organization of membrane proteins on B lymphocytes, focusing on their nanoscale arrangement and its implications for immune activation. It employs innovative techniques to study these structures, aiming to enhance understanding of immune responses and potential disease markers.
To detect foreign invaders and to communicate with other cells of the immune system, B lymphocytes carry a multitude of receptor proteins on their surface.
In the past, it was thought that most of these receptors are randomly distributed on the cell surface and only become organized upon lymphocyte activation.
Recent studies showed, however, that many of these surface proteins are pre-organized in nanoscale protein islands (here called nano-islands) with a size of 50-150 nanometer (nm).
We have…
ALBERT-LUDWIGS-UNIVERSITAET FREIBURG
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