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The NANOCANCER project investigates how high-atomic-number nanoparticles enhance the effectiveness of radiotherapy for glioma cells. By exploring both biochemical and physical effects, it aims to improve understanding of radiation sensitization and optimize treatment strategies.
The use of high-atomic-number nanoparticles (NP) as tumour radio-sensitizers has been recently proposed as a breakthrough in radiotherapy (RT).
Numerous biological studies have shown the enhanced effectiveness in tumor cell killing when NP were associated to photon RT and, more recently, to charged particle therapy.
However, the mechanisms of action are not clear yet.
In addition to the damage due to a possible local dose enhancement (physical effects), the interaction of NP with essential biolo…
CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON
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