CORDIS Project
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The project aims to develop a tool for single-cell proteomic analysis using a scanning ion conductivity microscope. This technology will allow real-time detection of proteins within live cells, providing insights into cellular processes in health and disease.
Presently there is a strong need to single-cell tools able to provide new insights into cellular proteome heterogeneity underlying dynamics, mechanisms and cell states in development and disease.
Of particular interest in this framework is the possibility to have an effective intra-cellular proteomic detection in live cells.
This mainly for three reasons: the first relates to preservation of higher protein concentration if the detection occurs before a molecule is dispersed in the extracellular…
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