CORDIS Project
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This research investigates the organization and triggering mechanisms of T-cells at the nanoscale using advanced microscopy techniques. It aims to enhance understanding of T-cell activation and interactions, which could lead to improved immunotherapy strategies.
The organization of the T-cell in its resting and activated state, specifically of plasma-membrane molecules involved in the triggering of the T-cell, is a long-standing and contentious research topic in molecular immunology.
Understanding the molecular mechanisms involved at the nanoscale, i.e. at spatial scales below the resolution limit of conventional optical microscopy (< 200 nm) will find answers to still open questions, and offer new routes to immunotherapy.
The proposed multidisciplinary…
UNITED KINGDOM RESEARCH AND INNOVATION
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United Kingdom, SWINDON
Type: Public body
Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
United Kingdom, Oxford
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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