CORDIS Project
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This project investigates the properties of amyloid proteins, which are linked to various human disorders, including Alzheimer's disease. Using advanced microscopy techniques, it aims to understand how the physical characteristics of amyloids affect their behavior and potential role in disease pathology.
The conversion of normally soluble and functional proteins into insoluble protein aggregates known as amyloids are linked to more than 50 human disorders, including several common forms of age-related dementia such as Alzheimer’s and Parkinson’s diseases.
Amyloids exist as long, rope-like structures known as fibrils which can self-associate into intractable plaques-a hallmark of many amyloid-related diseases.
Here we propose to investigate the potential role the material properties of amyloid, i…
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