CORDIS Project
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This research focuses on developing new therapies for glaucoma by targeting the metabolism of a key molecule, nicotinamide adenine dinucleotide (NAD). The project aims to create drug delivery systems that enhance NAD production to prevent neurodegeneration in the eye.
Metabolic decline may be a critical, and treatable, pathogenic component of glaucoma.
Glaucoma is one of the most prevalent neurodegenerations worldwide, affecting 80 million patients worldwide.
There are no neuroprotective therapies.We have discovered metabolic and mitochondrial dysfunction in the retina and optic nerve which occur prior to neurodegeneration in glaucoma.
One of these early changes is a decline in the important metabolite nicotinamide adenine dinucleotide (NAD), which critically…
KAROLINSKA INSTITUTET
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