CORDIS Project
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This project aims to study specific types of brain cells using advanced imaging and computational techniques. It seeks to understand the role of these cells in neural signaling and their contribution to cognitive functions, potentially informing new treatments for neurological disorders.
In the present proposal, we plan to examine the dendrites, axons, and presynaptic terminals of fast-spiking, parvalbumin-expressing GABAergic interneurons using subcellular patch-clamp methods pioneered by the PI, imaging techniques, and computational approaches.The goal is to obtain a quantitative nanophysiological picture of signaling in this key type of interneuron.
By incorporating realistic BC models into dentate gyrus network models, we will be able to test the contribution of this importa…
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