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NanoProt4Cond focuses on understanding biomolecular condensates in cancer biology, specifically through the Wnt signaling pathway. The project aims to engineer protein nanoparticles that can modulate condensate formation, potentially leading to new cancer treatment strategies.
Biomolecular condensates, formed by liquid-liquid phase separation (LLPS), play a pivotal role in diverse biological processes and diseases, including cancer.
Despite their importance, it is still a challenge to understand the role of condensates in biological regulation. ""NanoProt4Cond"" aims at exploring the Wnt signalling pathway, deregulated in cancers like colorectal cancer, using the cutting-edge high-throughput technology ‘PhaseScan’ to investigate condensate formation by Wnt-related pro…
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