CORDIS Project
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This project develops an ex vivo model of a whole porcine eye to evaluate periocular nanoformulations targeting the retina. It aims to provide a safer alternative to intraocular injections, reduce animal testing, and improve predictions of drug transport mechanisms in ocular tissues.
The incidence of chronic vision-impairing retinal diseases is increasing due to population ageing.
Monthly intraocular injections are the standard of care, despite the important risks (e.g., infection and haemorrhage) associated with this practice. A promising alternative is the periocular injection of nanocarriers, which are able to enhance the permeability across the ocular membranes.
However, as periocular administration relies on the drug transport mechanisms in the tissues to reach the targ…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Spain, Pamplona
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Israel, Tel Aviv
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Germany, Tuebingen
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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