CORDIS Project
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This project develops bioconjugated silicon nanoparticles and dual-emission fluorescent biosensors for studying protein conformation in cancer and neurodegenerative diseases. The aim is to create tools for detecting tumor cells and understanding protein aggregation processes.
This project integrates the development of (a) bioconjugated silicon nanoparticles (NPs) as new, < 3nm, fluorescent probes and (b) dual-emission band fluorescent biosensors for protein conformation investigations to be applied in diagnostic procedures related to tumor biology and neurodegenerative diseases.
Epidermal growth factor receptor (EGFR) is an important therapeutic target in a variety of tumors, particularly malignant gliomas where mutation and/or amplification of EGFR is often observed…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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