CORDIS Project
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This project investigates how the shape of phospholipid membranes, particularly their tubular structures, influences the movement and trapping of lipids and proteins in neuronal synapses. Using advanced imaging techniques, it aims to develop a model that incorporates membrane geometry into the understanding of molecula…
The aim of the proposed project is to understand how the morphology of the phospholipid membrane, and in particular tubular geometry and high curvature, affects the diffusion and trapping of lipids and membrane proteins in synaptic spines of neuronal cells.
This will be achieved by using a simplified in vitro system reconstituting artificial tubular membrane where the geometrical, physical and chemical parameters of the membrane can be closely controlled and varied and the diffusion of individua…
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