CORDIS Project
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This project focuses on understanding the role of bioactive N-Acylethanolamines in various diseases. It aims to investigate the enzyme responsible for their production and its potential as a target for drug development in conditions like inflammation and neurodegeneration.
Imbalances of human major lipid signaling pathways contribute to progression in inflammation, neurodegenerative and metabolic diseases.
Among lipidic messengers, the family of bioactive N-Acylethanolamines (NAEs) is agonist at cannabinoid and nuclear α-type peroxisome proliferator-activated receptors.
The ability of NAEs and their metabolic enzymes to modulate neurotransmission and a variety of pathophysiological processes, including inflammation, appetite, pain and mood, provides unique chances…
FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
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