CORDIS Project
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This project focuses on creating advanced nanodevices for early cancer detection and targeted drug delivery. By mimicking natural biological mechanisms, these devices will change shape in response to specific tumor markers, enhancing diagnostic accuracy and treatment effectiveness.
Late diagnosis and difficult treatment represent major obstacles in the fight against cancer. I propose here the development of self-regulated theranostic nanodevices supporting both early cancer diagnosis and targeted, tumor-cell-specific drug-release.
Specifically, I will exploit the “designability” of nucleic acids to design and optimize molecular nanodevices that undergo binding-induced conformational changes upon target binding and, in doing so, signal the presence of a specific tumor marke…
UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA
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