CORDIS Project
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The NaV1.5-CARED project focuses on understanding and restoring the function of a key sodium channel involved in heart rhythm regulation. By studying genetic factors and developing new therapeutic interventions, the project aims to provide alternatives to invasive treatments for cardiac arrhythmias.
The voltage-gated sodium channel (Na-channel;
NaV1.5) is a central component of cardiac electrogenesis.
Its dysfunction can lead to ventricular fibrillation and sudden cardiac death.
While NaV1.5 represents a highly relevant therapeutic target for prevention of life-threatening cardiac arrhythmias, therapies that target the expression or function of this channel are non-existent.
Such a therapy would provide for the first time an alternative for the invasive and costly cardioverter defibrillator…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
France, Nantes
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES
France, Nantes
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Netherlands, Amsterdam
Type: Research institute
Activity type: Research Organisations
SME: No
France, Saint-Egreve
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: No
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